Disintegration

Extraction

Phase separation

    Sedimentation

   Centrifugation  

   Filtration

Concentration

Diafiltration

Chromatography

Formulation

Critical Quality Attributes

Unit Operation

Process Parameters

Parameters Interaction

Design Space

Linking of Unit Operation

Unit Operation Sequence

Scale Up

 

 

 

 

Process

   PAT

  Stability studies

  Verification

  Validation

Analysis

  Validation

Equipment

  Validation